In cancer, AI has shown great promise in characterizing tumors, suggesting appropriate treatments and predicting patient survival. Despite the large potential impact on patient well-being and outcome, a digital health research platform, integrating multimodal data and advanced analytics, is slow to emerge, not in a small part due to (legal) data privacy restrictions. In the TumorScope project, the unique expertise and data present at the VUB and the UZ Brussel is put in a general framework to store and analyze raw medical data, both at the image and molecular level, in relation to solid tumors, their clinical behavior and response to therapies.